Over40.it, our new e-zine dedicated to you, a splendid over forty-years-old woman who looks at life as the best part is here and now.

Friday, February 20, 2009

Live longer with resveratrol

there's no magic wand for completely preventing aging or common diseases such as diabetes, but resveratrol supplements may be the next best thing.
from Better Nutrition, Feb, 2009 by Jack Challem

THE BASICS: Resveratrol (pronounced res-vair-uh-traul) is an antioxidant found in small amounts in purple grapes, red wine, blueberries, and other fruits. What distinguishes it from all other antioxidants is its ability to promote health or longevity in a wide range of animals, from microscopic worms to human beings. In animal studies, resveratrol increases life expectancy--even when animals eat a junk food diet. It also appears to have some benefits in regulating blood sugar and reducing the risk of heart disease.

ALIAS: Resveratrol is a polyphenolic antioxidant, part of a large family of related chemicals found in the skin of fruits. Research originally focused on resveratrol extracted from red wine, but most resveratrol supplements now come from lapanese knotweed (Polygonum cuspidatum).

HOW RESVERATROL WORKS: Resveratrol increases the activity of SIRT1, a key gene involved in longevity in numerous species, including humans. By boosting SIRT1 activity, resveratrol has many collateral benefits in reducing the risk of age-related diseases, including diabetes, heart disease, and cancer. Unfortunately, almost all of the research has been done in test tubes, and with yeast, worms, fruit flies, fish, and mice--not people. That said, the single human study with resveratrol found promising benefits.

HEALTH BENEFITS: Resveratrol seems to benefit several age-related health problems.

* Antiaging. In studies conducted at Harvard University, mice getting supplemental resveratrol had higher activity of the SIRT1 gene. They also had lower levels of insulin-like growth factor-l, considered a risk factor for cancer. The mice also lived about 15 percent longer (the equivalent of 11 human years) compared with mice that were not fed resveratrol. Even with advancing age, the mice maintained physical activity and coordination more like that of younger mice. The benefits were all the more striking because the mice were red the equivalent of a junk food diet.

* Diabetes. The Harvard University researchers also found that mice eating a high-calorie diet and taking resveratrol did not develop diabetes; however, animals not getting the antioxidant did develop the disease. In a small study of men with type 2 diabetes, resveratrol supplements reduced fasting blood sugar levels and improved insulin function. Diabetes is known to accelerate the aging process. A second study using resveratrol to treat people with diabetes is under way.

* Heart Disease. Animal studies suggest that resveratrol may lower the risk of heart disease. Resveratrol has anti-inflammatory properties--important because heart disease is now considered an inflammatory disease of the arteries. Resveratrol may also prevent oxidation of cholesterol, regarded as an early step in the development of heart disease. Additionally, resveratrol has a mild blood-thinning effect, which would reduce the risk of blood clots.

* Cancer. Growing evidence suggests that resveratrol might have a role in cancer prevention. Resveratrol seems to prevent different stages of cancer growth and reduce cell division and metastasis, according to an article in Cell Cycle. Seven studies using resveratrol as an adjunct in the treatment of cancer in people are under way, but the results won't be known for several years.

BACKGROUND CHECK: Resveratrol was first isolated from plants in 1940. It didn't attract attention for its antiaging properties until the 1990s.

GLEANINGS: Fresh purple grape skins provide 50 to 100 mg of resveratrol per gram; one-quarter pound of grapes should provide more than 8,000 mg of resveratrol.

HEADS UP: The pharmaceutical industry is taking resveratrol very seriously. In 2007, drug giant GlaxoSmithKline paid $720 million to buy Sirtris Pharmaceuticals. Sirtris researches resveratrol and has been trying to develop synthetic versions of the chemical.

WHAT YOU SHOULD TAKE: A recent study found impressive benefits from the equivalent of about 300 mg daily of resveratrol. That amount can still be pricey as a supplement, so a reasonable compromise might be taking 100 mg of resveratrol as a single supplement, of with a high-potency multivitamin of multi-antioxidant formula.


Some reports suggest that muscadine grapes have a higher concentratmn of resveratrol than other types of grapes; muscadine grape juice and supplements are at health food stores.

resveratrol helps Bill manage his blood sugar

Bill was recently diagnosed with type 2 diabetes and was trying to control his blood sugar as much as possible with nutritional supplements. Several supplements proved helpful, including chromium, vitamin D, and biotin. However, he still needed to take a glucose-controlling medication prescribed by his physician.

Then Bill happened to read about resveratrol, an antioxidant that seems to increase longevity. He knew that diabetes would accelerate aging because of tissue damage from high levels of blood sugar and insulin. So he started taking resveratrol supplements, 100 mg in the morning and another 100 mg in the evening. To his pleasant surprise, his fasting blood sugar decreased 10 mg/dL, a change that moved him from being diabetic to Prediabetic. Because of this improvement, he was able to lower his medication requirements.
COPYRIGHT 2009 PRIMEDIA Intertec, a PRIMEDIA Company. All Rights Reserved.

Just arrived at GNC: as seen on 60 minutes
Biotivia Bioforte Resveratrol: linkicon

Monday, February 16, 2009

12 supplements that help us stay young and healthy

Do you know what epigallocatechin is? Or singlet oxygen and peroxynitrite? Ever heard of alpha-lipoic acid and ORACs? This seemingly foreign language is the key to your health. But it doesn't have to be foreign. What are these invisible friends and foes anyway?

Free radicals, the enemy within
Without the right protection, the Tin Man in the Wizard of Oz would have rusted away. And without antioxidants protecting us from the relentless attack of free radicals, we would rust on the inside, develop disease, and die young. While practically everyone wants something free, you certainly don't want these. Free radicals are vicious molecules missing an electron in their outer shell. Most are toxic forms of oxygen molecules. These unstable gangsters steal electrons from healthy cells, rendering them "biologically rusted," damaged, or destroyed. Free radicals spawn from environmental pollution, toxins, pesticides, chemicals, sunlight, radiation, food, drink, and metabolic activity in the body. These injurious free radicals destroy living tissue and fluids. They rapidly accelerate the aging process, severely damaging the ability of the immune system to battle unwanted pathogens (e.g. bacteria, viruses, and parasites) that enjoy invading your body. According to noted biochemist Richard Passwater, Ph.D., free radicals are "biological terrorists" of the human terrain.

Antioxidants are bio-police working 24/7
As free radical molecules cause oxidation, biological rusting continues inside the body. Antioxidants labor tirelessly to slow down and terminate this oxidation process. These kamikaze life-saver molecules continually seek and destroy free radicals, sacrificing themselves and self-destructing, to save other healthy cells from certain death. Catechins, which are abundant in green tea, are an example of antioxidants that readily allow themselves to be oxidized in place of more essential molecules in the body. Some antioxidants, like the proanthocyanidins (found in grapeseed and French maritime pine bark extracts) work to regenerate vitamin C, which then regenerates vitamin E.

Plants - where the antioxidant action is

The plant kingdom is home to thousands of body-friendly antioxidants identified by botanists, biologists, and biochemists. Thousands, perhaps millions more yet unknown, wait to be discovered. Appropriately dubbed phytonutrients ("phyto," meaning plant), these nutrients have names like bioflavonoids, polyphenols, and carotenoids.

12 dietary supplements that can keep you young and healthy

1. Alpha-lipoic acid is a unique water and fat-soluble antioxidant capable of quenching many more free radicals than only water or fat-soluble antioxidants. It recycles vitamins C and E, and glutathione, while scavenging and destroying free radicals.

2. Lycopene is the red carotenoid found in tomatoes, red grapefruit, apricots, and watermelon. This incredibly aggressive antioxidant has been the subject of much recent research positively validating its free radical quenching and cancer preventive abilities.

3. Indole carbinol 3 and sulforaphane stimulate the production of carcinogen killing enzymes. They are plentiful in Brussels sprouts, kale, collard greens, broccoli, mustard greens, cabbage, and cauliflower.

4. Alpha-tocopherol is commonly known as vitamin E, one of eight forms found in the vitamin E complex. Four are tocopherols, possessing antioxidant activity that has been validated in thousands of studies. Four are tocotrienols, cousins to vitamin E, which support the activity of alpha tocopherol. Olives, nuts, and seeds are rich sources.

5. Vitamin C, found in citrus fruits, tomatoes, peppers, broccoli and hot red peppers, is the primary water-soluble antioxidant in the body. Thousands of studies clearly support vitamin C's ability to protect against free radical damage. Because we cannot produce vitamin C internally, we must obtain it from food and supplemental sources.

6. Beta-carotene is one of over 600 carotenoids noted for their effectiveness at quenching singlet oxygen and other free radicals.

7. Vitamin A, the "anti-infective," maintains skin, respiratory tract surfaces, mucous membranes, and secretions, thereby reducing free radical activity generated by infection. Vitamin A converts from beta-carotene in the liver, stimulating production of white blood cells.

8. Lutein, discovered in marigolds, is best known as the eye antioxidant, preventing macular degeneration.

9. Beta 1,3-D glucan, a polysaccharide (sugar) found in yeast-cell walls and maitake mushrooms, stimulates free radical scavenging ability of natural killer cells and macrophages in the immune system.

10. NAC (n- acetyl cysteine) is an amino acid derivative that is a precursor to glutathione, the essential and most effective antioxidant in the liver.

11. SOD (superoxide dismutase), an antioxidant enzyme, prevents damage from the superoxide radical, the most common free radical we encounter.

12. Selenium is a trace mineral. Although, according to some purists, not technically an antioxidant, itself, it is generally considered one because it is essential to the formation and replenishment of the powerful free radical scavenger glutathione.

Don't forget these antioxidants
The anti-aging antioxidant ellagic acid is found in grapes, wine, berries, walnuts, apples, tea, and pomegranates. Bilberry is rich in blue-colored polyphenols that have exceptional antioxidant activity in the eyes. Epigallocatechin gallate, plentiful green tea, is perhaps more potent than any other antioxidant.

Stayin' alive with phytofood ORACs
Antioxidants are gifted with the unique ability to absorb and destroy free radicals, rendering them harmless. Breakthrough research at the USDA Human Nutrition Center for Aging at Tufts University in Boston, Massachusetts conducted by Ronald Prior, Ph.D., and his researchers uncovered and evaluated the specific free radical absorbing capacity of fruits and vegetables. This powerful capacity to absorb and neutralize free radicals was measured in what scientists call ORAC units (Oxygen Radical Absorbance Capacity). So what's the big deal? Specifically, this tells us how aggressively antioxidants in a fruit or vegetable destroy free radicals circulating throughout the body, and how effectively they prevent cell damage and anti-aging. Take our advice on this one -- eat and drink them every day!

There's more,

Garlic and onions are loaded with organosulfur compounds that stimulate the production of glutathione s-transferase, a powerful detoxifying enzyme in the liver.

Phytic acid found in rye, wheat, rice, lima beans, sesame seeds, peanuts, and soybeans is an intense free radical gobbler.

Barley grass juice, a super nutritious green beverage contains "2-O-GIV" (2-0-glycosylisovitexin), an aggressive inhibitor of lipid peroxidation (oxidation of fat). Other green juices, specifically wheat grass juice, teem with antioxidants that rival all the others. While antioxidants will not enable us to live forever, they can certainly increase our odds of living a long and healthy life. Get your fountain of youth arsenal together today. Head to the health food store for those turn-back-the-clock antioxidant supplements. Eat 5 to 10 servings of fruits and vegetables each day. Have a refreshing green drink. Munch on those prunes. And drink your grape juice. A glass a day keeps old age away!

COPYRIGHT 2000 PRIMEDIA Intertec, a PRIMEDIA Company. All Rights Reserved.

Thursday, February 12, 2009

Look 10 year younger by losing the unwanted weight.

Skincare, wellness, health are all good chores in the program of looking 10 years younger. We discovered a website that explains how to easily lose the unwanted waste and maintain the new healthier achieved weight in an easily manner. This program is hot in the press, but the sussess stories are what made us decide to give it a try!

Smart for Life™ (URL: www.the-cookiediet.com) has helped hundreds of thousands of people lose millions of pounds for better health, appearance and happiness. They offer consumers a perfectly balanced fruit, protein, fiber and vegetable cookie that truly is a meal that can be carried anywhere! In addition to their Smart Cookies, they also offer consumers a variety of weight-loss shakes, muffins, and soups. Perfect for our hectic lifestyles!

Let's show what we intend with "success stories":

This is Monique before and after: she lost 106 pounds and looks 15 years younger!
Eat Cookies Lose Weight Eat Cookies Lose Weight

Steve lost 115 and now looks like the successful manager he is!
Eat Cookies Lose Weight Eat Cookies Lose Weight

Leora lost 141 pounds and now she looks gorgeous in total black!
Eat Cookies Lose Weight Eat Cookies Lose Weight

Kristin lost over 134 pounds - isn't she hot?
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Robin lost over 63 pounds and now looks like he's his own son!
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Applause to Laura who lost over 167.5 pounds!!!!
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Thousands of SMART FOR LIFE™ clients have taken control of their health and with the SMART FOR LIFE™ Foods, reached their ideal weight. Best of all, they have maintained the weight loss. Whether it’s on their own or with the support of a local, participating SMART FOR LIFE™ Center, these clients have completed their weight loss goals and have become SMART FOR LIFE™! As they say: "Eat Cookies, Lose Weight! It's that Simple!"
Click here for more info.

Monday, February 9, 2009

Buy one get one Free prescription eyeglasses

Buy one get one Free 24 Hour Clearance Sale
Eye Buy Direct is a leading provider of high quality prescription eyeglasses and sunglasses at amazing values: Enjoy their "Buy one get one Free 24 Hour Clearance Sale" here!
Valid 2/9/09 only!!!

via |Coupons' Choice

Friday, February 6, 2009

Martha's Beauty Must Haves

Enjoy Martha's favorite beauty products from skincare guru Mario Badescu, now with FREE SHIPPING on any order over $30! Offer valid until 02/12/2009.

As seen on the Martha Stewart Show:

A.H.A. Botanical Body Soap (16 oz.)
Martha loves: A.H.A. Botanical Body Soap (16 oz.) - $ 14.00
The AHA Botanical Body Soap is enriched with fresh Fruit Extracts to exfoliate and cleanse the skin. Papaya and Grapefruit Extracts help to breakdown dead skin cells and leave skin looking healthy. Ginseng Extract rejuvenates while Oat Protein soothes sensitive and irritated areas. Excellent choice for those with problem skin on the back, chest and shoulders.

Citrus Body Cleanser (8 oz.)
Martha loves: Citrus Body Cleanser (8 oz.) - $ 10.00
Grapefruit Extract gently exfoliates the skin while the soothing properties of Linden Flower help to leave the skin feeling clean and refreshed.

Facial Spray With Aloe, Herbs And Rosewater (8 oz.)
Martha loves: Facial Spray With Aloe, Herbs And Rosewater (8 oz.) - $ 12.00
A refreshing, hydrating mist to use anywhere anytime. Formulated simply with fragrant Herbal Extracts and Rosewater for a pleasant, pick me up for dehydrated, tight and uncomfortable skin. Spray your day and night creams for a boost of hydration or use it to set make-up or spray on dry hair throughout the day. Safe for all skin types, gentle, non-irritating.

Special Hand Cream with Vitamin E (8 oz.)
Martha loves: Special Hand Cream with Vitamin E (8 oz.) - $ 14.00
Rich, non-greasy formula of Vitamin A, Vitamin E, Wheat Germ Oil and Honey hydrates dry, cracked hands.

via | Martha Stewart Fans